INFLUENCE OF GENETIC VARIATIONS IN PHYSICAL FITNESS

Abstract

Older population has increased and presents reduced physical fitness. On the other hand, it is known that genetic variants can explain these declines. The aim of this study was evaluate the effect of ACE ID and ACTN3 R/X polymorphisms in body fat and physical capacities in old women. 66 old women were genotyped to ACTN3 and ACE polymorphisms and submitted to anthropometric measurements, physical tests, IPAQ and a questionnaire related to food intake. For the ACTN3 genotype, XX group presented reduced levels of upper limb flexibility and cardiorespiratory capacity. Related to ACE genotype, ID group demonstrated increased cardiorespiratory capacity and decreased body fat percentage. There was no statistical difference in the other variables. In the future, data like these will enable each person have his/her intervention focused in that variables with more genetic potential to decline.